Multi-tire transport semi-trailer can complete the transport of overweight, overheight, overlength, overwidth or materials with special transport requirements, and has the advantages of high efficiency, low consumption, flexibility and so on, and it is suitable for the transport of bulky goods. Multi-tire transport semi-trailer adopts frame-type loading platform, mechanical-hydraulic all-wheel steering or power steering, hydraulic balanced independent suspension, all-round swinging integral axle, three-point or four-point support, and double-pipe all-wheel brakes, which has the advantages of adjustable height of the cargo platform, even axle loading, small turning radius, convenient reversing, etc. It can be widely used in the transport of large and difficult-to-dismantle cargoes in the fields of petroleum, chemical industry, mining management, wind power generation, construction, earthmoving and so on. It can be widely used in petroleum, chemical, mining, wind power generation, construction, earth moving construction and other large and difficult to dismantle goods.